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Category: Personal blog

Personal blog / Tutorials

Exploring the Capabilities of ChatGPT: A Step-by-Step Guide to Creating a Pharmacokinetic Analysis Shiny App

With the introduction of ChatGPT I was interested to learn how ChatGPT in pharmacometrics might be applied and how this will impact my code writing tasks, especially for doing pharmacokinetic …

Personal blog

Introduction to pharmacometrics and its importance in drug development

Pharmacometrics is a rapidly growing field that combines pharmacology, mathematics, and statistics to optimize drug development and dosing. It is the science of quantifying drug effects in patients and developing …

Personal blog

Abbreviations and Terminology Used in Population Pharmacokinetics/Pharmacodynamic Models and in Pharmacometrics

This page provides an overview of the abbreviations and terminology commonly used in population PK/PD articles.

Personal blog

Publishing the covariance matrix of population models. Why not?

The information in the covariance matrix Everyone that has worked for longer than a day with NONMEM has a high probability of encountering error messages mentioning the covariance matrix (nonpositive …

Personal blog / Tutorials

How (not) to report pharmacokinetic data

The correct reporting of pharmacokinetic data can provide a tremendous amount of information on the clinical pharmacological characteristics of a drug. Small studies with a limited number of plasma samples …

Personal blog

Celebrating 15.000 visitors by going open source!

In 2019 alone, PMXSolutions.com has been visited by over 15.000 visitors! In order to celebrate this overwhelming interest in the website, I have made the Shiny application for pharmacokinetic simulations …

Recent posts:

  • Exploring the Capabilities of ChatGPT: A Step-by-Step Guide to Creating a Pharmacokinetic Analysis Shiny App
  • Using R Shiny applications in scientific research – Can you spot a drug effect on blinded pharmacodynamic data…?
  • Introduction to pharmacometrics and its importance in drug development
  • New shiny applications for PMX simulations!
  • Abbreviations and Terminology Used in Population Pharmacokinetics/Pharmacodynamic Models and in Pharmacometrics
  • Publishing the covariance matrix of population models. Why not?
  • Parallel fast-slow absorption – Modelling the Tortoise AND the Hare
  • Applying MAP Bayes estimation for therapeutic drug monitoring (TDM) in R with mrgsolve
  • Simulating the equi-dosing regimen region in R using mrgsolve – a bottom-up approach
  • How (not) to report pharmacokinetic data
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