Execute NONMEM models via the right-click menu (with user specified commands)
Wouldn’t it be nice to have this option when you click on a model file: It can be quite a hassle to start the execution of your NONMEM models. Luckily, …
Wouldn’t it be nice to have this option when you click on a model file: It can be quite a hassle to start the execution of your NONMEM models. Luckily, …
It is difficult to grasp what non-linear mixed effects modelling software is actually doing when you start a run. Furthermore, the iteration prints that you see in the console (when …
This blog is an extension on the previously discussed scatter VPC. A percentile visual predictive check (VPC) can be used to compare the distribution of the observations with the simulated distributions …
When you start to use NONMEM, the first thing that you notice is that there is no graphical user interface (GUI) that comes with it. This can be a shock …
Last time, we focused on the percentile VPC, which was already quite an improvement to the scatter VPC but one may wonder when looking at a percentile VPC, how certain …
There are many different ways to evaluate model performance, and sometimes it seems that there are even more ways to use a visual predictive check (VPC) for your population PK …
Model evaluation is a critical step in model development. A very good paper on how to evaluate continuous data pharmacometric models was published by Nguyen et al. in 2017, this …