New shiny applications for PMX simulations!

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A range of new shiny applications have been published on this website to visualise pharmacokinetic profiles over time and better understand the use of population models. All applications can be accessed from the Applications menu on this website.

All code is updated on GitHub

https://github.com/michielve

PK profile over time

Simulate an oral pharmacokinetic profile based on the dose and model parameters. Profiles can be saved in a session to explore the profiles of different parameters sets

Therapeutic window simulations

Based on a range of model parameters covering both intravenous and oral administration, simulate a multiple dose pharmacokinetic profile and calculate the time within the pre-specified therapeutic window at steady state.

Therapeutic window (with IIV)

Based on a range of model parameters covering both intravenous and oral administration, simulate a multiple dose pharmacokinetic profile and calculate the time within the pre-specified therapeutic window at steady state. The CV% (inter-individual variability) on the clearance and volume of distribution parameter can be modified to simulate a population.

2 thoughts on “New shiny applications for PMX simulations!”

  1. Liu Xiaolin Reply

    Hi, can you please tell me how to change the Therapeutic window range in the plot？

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