With the introduction of ChatGPT I was interested to learn how ChatGPT in pharmacometrics might be applied and how this will impact my code writing tasks, especially for doing pharmacokinetic …
A range of new shiny applications have been published on this website to visualise pharmacokinetic profiles over time and better understand the use of population models. All applications can be …
This page provides an overview of the abbreviations and terminology commonly used in population PK/PD articles.
Introduction Unsurprisingly, the absorption of drugs is a complex process. Should you try a first-order input? Zero-order? Both?! Especially when a bias in the model fit of your absorption phase …
Acknowledgments The idea for this post was based upon the research by Dr. Lloyd Bridge, presented at the British Pharmacological Society meeting December 2018. and published in October 2020 in …
The correct reporting of pharmacokinetic data can provide a tremendous amount of information on the clinical pharmacological characteristics of a drug. Small studies with a limited number of plasma samples …
How do we develop a ‘standard’ population PK model? We obtain blood/plasma concentrations over time of the drug of interest, in multiple individuals, and we apply our population NLME modelling …
Shiny applications are a great way to show your complicated models in an interactive way. In recent years, many different examples have been published online showcasing a wide range of …
This two part series will show you how to create a simple pharmacometric Shiny application using the mrgsolve package in R. I think that Shiny applications are the most promising way …
