In the pursuit of ethical and efficient drug development, the scientific community continues to embrace the 3R’s principle — Replacement, Reduction, and Refinement — to minimize the use of animals …
A non-compartmental analysis (NCA) is commonly performed to analyse the data of a pharmacokinetic study. It is an easy way of getting your pharmacokinetic parameters (such as the Cmax, tmax, …
In 2022 I was working as a senior pharmacometrician (primarily focused on clinical phase 1/2a PK/PD and scientific research) when I was contacted by a recruiter on LinkedIn to apply …
I love to listen to podcasts while I am working out or going for a walk. However, I must admit that some of these podcasts are just a background conversation …
With the introduction of ChatGPT I was interested to learn how ChatGPT in pharmacometrics might be applied and how this will impact my code writing tasks, especially for doing pharmacokinetic …
Shiny applications are commonly used as a data dashboard, to automate a (data science) workflow, or to easily build a minimum viable product. Shiny is a great tool if you …
Pharmacometrics is a rapidly growing field that combines pharmacology, mathematics, and statistics to optimize drug development and dosing. It is the science of quantifying drug effects in patients and developing …
A range of new shiny applications have been published on this website to visualise pharmacokinetic profiles over time and better understand the use of population models. All applications can be …
This page provides an overview of the abbreviations and terminology commonly used in population PK/PD articles.
The information in the covariance matrix Everyone that has worked for longer than a day with NONMEM has a high probability of encountering error messages mentioning the covariance matrix (nonpositive …
