Abbreviations and Terminology Used in Population Pharmacokinetics/Pharmacodynamic Models and in Pharmacometrics
This page provides an overview of the abbreviations and terminology commonly used in population PK/PD articles.
This page provides an overview of the abbreviations and terminology commonly used in population PK/PD articles.
The information in the covariance matrix Everyone that has worked for longer than a day with NONMEM has a high probability of encountering error messages mentioning the covariance matrix (nonpositive …
It is difficult to grasp what non-linear mixed effects modelling software is actually doing when you start a run. Furthermore, the iteration prints that you see in the console (when …
This blog is an extension on the previously discussed scatter VPC. A percentile visual predictive check (VPC) can be used to compare the distribution of the observations with the simulated distributions …
Last time, we focused on the percentile VPC, which was already quite an improvement to the scatter VPC but one may wonder when looking at a percentile VPC, how certain …
There are many different ways to evaluate model performance, and sometimes it seems that there are even more ways to use a visual predictive check (VPC) for your population PK …
Model evaluation is a critical step in model development. A very good paper on how to evaluate continuous data pharmacometric models was published by Nguyen et al. in 2017, this …