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Tag: Simulation

Personal blog

Publishing the covariance matrix of population models. Why not?

The information in the covariance matrix Everyone that has worked for longer than a day with NONMEM has a high probability of encountering error messages mentioning the covariance matrix (nonpositive …

Tutorials

Applying MAP Bayes estimation for therapeutic drug monitoring (TDM) in R with mrgsolve

The development of population PK (and PD) models enable the use of individual Bayesian dose optimization. One could use the included covariates to derive the dose of an individual but …

Recent posts:

  • Learn about pharmacometrics and clinical pharmacology during your workout
  • Exploring the Capabilities of ChatGPT: A Step-by-Step Guide to Creating a Pharmacokinetic Analysis Shiny App
  • Using R Shiny applications in scientific research – Can you spot a drug effect on blinded pharmacodynamic data…?
  • Introduction to pharmacometrics and its importance in drug development
  • New shiny applications for PMX simulations!
  • Abbreviations and Terminology Used in Population Pharmacokinetics/Pharmacodynamic Models and in Pharmacometrics
  • Publishing the covariance matrix of population models. Why not?
  • Parallel fast-slow absorption – Modelling the Tortoise AND the Hare
  • Applying MAP Bayes estimation for therapeutic drug monitoring (TDM) in R with mrgsolve
  • Simulating the equi-dosing regimen region in R using mrgsolve – a bottom-up approach
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