In the pursuit of ethical and efficient drug development, the scientific community continues to embrace the 3R’s principle — Replacement, Reduction, and Refinement — to minimize the use of animals …
In 2022 I was working as a senior pharmacometrician (primarily focused on clinical phase 1/2a PK/PD and scientific research) when I was contacted by a recruiter on LinkedIn to apply …
I love to listen to podcasts while I am working out or going for a walk. However, I must admit that some of these podcasts are just a background conversation …
With the introduction of ChatGPT I was interested to learn how ChatGPT in pharmacometrics might be applied and how this will impact my code writing tasks, especially for doing pharmacokinetic …
Pharmacometrics is a rapidly growing field that combines pharmacology, mathematics, and statistics to optimize drug development and dosing. It is the science of quantifying drug effects in patients and developing …
This page provides an overview of the abbreviations and terminology commonly used in population PK/PD articles.
The information in the covariance matrix Everyone that has worked for longer than a day with NONMEM has a high probability of encountering error messages mentioning the covariance matrix (nonpositive …
The correct reporting of pharmacokinetic data can provide a tremendous amount of information on the clinical pharmacological characteristics of a drug. Small studies with a limited number of plasma samples …
In 2019 alone, PMXSolutions.com has been visited by over 15.000 visitors! In order to celebrate this overwhelming interest in the website, I have made the Shiny application for pharmacokinetic simulations …
